Event Overview

Achieving excellence with R&D data will enable the life sciences industry to increase the speed and quality of innovation and is thus a major source of competitive advantage. Whether researchers and informaticians deal with “big data,” “deep data” or just put their data to smarter use, it is clear that the future of R&D is dependent on both smart technologies and clever researchers. The rapid progress of innovation in software and powerful hardware now allows human researchers to interpret masses of raw data in unique ways and is redefining the R&D business model. The benefits range from discovery and “omics” research, through to clinical trials and to real patients in the real-world. However, it is major technical, financial, and operational challenge is to turn “messy” data into structured data, that can be used for advanced analytics that can spot opportunities and achieve true insights. Some of the most promising areas of technological innovation making rapid progress include, for example, artificial intelligence, machine learning, cloud computing and the blockchain (distributed ledgers). There is also huge potential for efficient collaborations between the life science industry, technology companies, academic researchers, health systems, physicians, and health insurers to remove data silos. A deeper convergence between key stakeholders and advanced technologies will facilitate the discovery and development of powerful therapies, devices and advanced diagnostics to benefit patients.

The “R&D Data Intel Leaders Forum” is the must attend event for those senior decision-makers, researchers, data scientists and technologists, looking to make the shift towards an integrated R&D and data strategy and for those looking to improve their implementation of data-driven approaches to enhance R&D specific decision-making and intelligence.

Speakers List

Pharma Industry

Director External Innovation, Oncology
Roche, Germany

Chief Scientific Officer
ERYTECH Pharma, France

VP & Head of Early Biometrics and Statistical Innovation, Data Science and AI
AstraZeneca

Head of Computational Life Science IT
Bayer

Senior Director Computational Biology, Discovery Sciences
Janssen Research & Development

Senior IT Project Manager Specialized in Health IT
Roche, Switzerland

Head of R&D G3O
Janssen, Belgium

Eike Staub

Director, Head of Oncology Bioinformatics
Merck

VP, Head of External Innovation Therapeutics
Bayer, Germany

Head of Decision Science, Digital Transformation & IT
Bayer

Senior Investigator II, Modeling & Simulation, Data Science
Novartis

Global Head of IT & Digital Transformation
Bayer, Germany

ML/AI Lead, R&D Informatics, Small Molecule Discovery Informatics
Roche

Biotechs

CSO
Tecrea, UK

CSO/COO
Oncodesign, France

Head of Translational Medicine and Bioinformatics
Agenus

MedTech & Diagnostics

CIO
Hartmann Group, Germany

Global Head of Technology & Innovation Management
Siemens Healthcare

External Stakeholders

Professor of Pharmaceutical Technologies
University of Greenwich, UK

Co-Director Noncoding RNA Core
Institute for RNA medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, USA

Founder
Institute for Interdisciplinary Innovation in healthcare, Université Libre de Bruxelles, Belgium

EU AI High Level Expert Group Member
Founder & CEO, OKRA Technologies

Technology Companies

Regional Business Leader Health and Life Sciences EMEA
Microsoft

Data Analytics Specialist
Google Cloud, Switzerland

CEO and Co-Founder
Phenomic AI

Head of Strategy
Horizon Discovery, UK

Event Structure

Photo Gallery

Event Program

Strategic Developments in R&D Innovation

Day 1 - 27th January, 2020

Stream Overview

Data is redefining the R&D model and enabling better decision-making and innovation. Senior-level thought leaders from both the R&D and technology perspectives will be presenting the best technologies and approaches of today which are already creating a proven impact in R&D and which will be crucial for the research demands of tomorrow. These speakers will also discuss which technological, financial, regulatory, and operational challenges need to be overcome to ensure that key insights are achieved, and that patients’ benefits are dramatically enhanced through R&D intelligence.

Registration & Coffee
08.30
Chairperson’s Opening Remarks
09.00

VP & Head of Early Biometrics and Statistical Innovation, Data Science and AI
AstraZeneca

What are the next steps in the evolution of R&D?

How digitalisation in healthcare could help save lives
09.10
  • Where does healthcare stand in terms of digitalisation 
  • What are the main challenges in digital healthcare?
  • How digitalisation could help overcome these challenges
  • What are the main technology trends in healthcare?

CIO
Hartmann Group, Germany

Empowering life sciences with explainable AI
09.40
  • Empowering life science executives to make decisions is the goal
  • For every prediction or suggestion that AI makes we must be able to explain where it came from
  • Without explainability being a fundamental part of AI outputs we cannot scale across this technology in Life Sciences
 

EU AI High Level Expert Group Member
Founder & CEO, OKRA Technologies

Networking & Coffee Break
10.40
Building the future of innovation in Pharma and Biotechs
11.10

What are the future strategic developments in Pharma and BioTech companies? How to bring medical research to the next level? Although healthcare companies have started to heavily invest on R&D innovation programs to ensure that they “reach the future”, the impact on those strategies on their day-to-day business has been relatively poor so far. Healthcare needs to offer “more value” for “less money” and “in less time”. The talk will explore a few ideas on how to help healthcare companies to streamline their R&D efforts (including the introduction of artificial intelligence) and bring innovation to the market faster.

Data Analytics Specialist
Google Cloud, Switzerland

Statistical innovation in early clinical development
11.40

VP & Head of Early Biometrics and Statistical Innovation, Data Science and AI
AstraZeneca

Precision medicine: Technology and innovation in the time of data science
12.10
  • How are science and technology converging in the healthcare space?
  • What collaboration modalities are emerging?
  • What are the leading technological megatrends?
  • Doing good and doing right in the age of precision medicine.

Global Head of IT & Digital Transformation
Bayer, Germany

Luncheon Break
12.40
Strategic innovation management and partnership for driving R&D
13.40
  • Integrated diagnostic and therapeutic decision making along clinical pathways
    • Technology convergence
    • AI
    • Diagnostic imaging & molecular technologies
    • Integrated pathways
    • Patient journey

Global Head of Technology & Innovation Management
Siemens Healthcare

Operationalising your R&D digital strategy: From multiple failures to impact and success
14.20

Head of Computational Life Science IT
Bayer

Networking & Coffee Break
15.00

INNOVATIVE APPROACHES TO R&D STRATEGY

New therapeutic options in Oncology: Innovation by using human red blood cells to treat cancer
15.30
  • Clinical efficacy for Asparaginase-loaded red blood cells in cancer tumor starvation
  • Utilizing natural red blood cell trafficking to build a highly differentiated immuno-therapy platform
  • Erythrocyte-encapsulated proteins for enzyme-based therapies
  • Pro & cons of having a real unique R&D platform

Chief Scientific Officer
ERYTECH Pharma, France

Medical Data: What about empowering the patients while keeping their identity well protected?
16.10
Presentation on the feasibility and benefits of creating a vendor/pharma independent, open source, Blockchain network to keep the real identity of the patients protected while allowing the possibility to:
  • Inform patients on the outcome of the research they participated in and inform them on how their data is supporting novel medical research;
  • Seek additional patient consent;
  • Seek additional information from patients on treatment outcome;
  • Empower the patients to choose which of their data can be used for what medical research
  • Facilitate Data Sharing
  • Establish a protected communication with the patient  
 

 

Senior IT Project Manager Specialized in Health IT
Roche, Switzerland

Panel Discussion: Technology and the future of medicine
16.50
  • R&D Innovation – External vs. Internal and where are the future blockbuster drugs coming from?
  • What are the key attributes of the future, visionary R&D leaders?
  • Data-driven drug development: Establishing strategy & data governance for an effective use of big data in the R&D process.
  • Harnessing the power of precision medicine and genomics through converging technologies.
  • AI and its impact on future of life sciences.

Head of Computational Life Science IT
Bayer

Senior IT Project Manager Specialized in Health IT
Roche, Switzerland

Global Head of Technology & Innovation Management
Siemens Healthcare

Data Analytics Specialist
Google Cloud, Switzerland

EU AI High Level Expert Group Member
Founder & CEO, OKRA Technologies

Closing remarks
17.20
End of day 1
17.30

18.30 NETWORKNG DINNER

External Innovation for Enhancing R&D

Day 2 - Stream 1 - 28th January, 2020

Stream Overview

This stream is focused on how pharmaceutical innovation can be enhanced through intelligent and novel external collaborations. Almost all pharma and medtech companies now believe that they key to innovation is not purely through performing R&D in-house, but through partnerships with biotechs, academic or government institutes to tap unique sources of knowledge, capabilities, resources and technologies. However, there are a myriad of different models of external collaborations, which may include classical one-on-one partnerships, but increasingly unique “open-innovation” or partnering with larger-scale R&D consortia to pool risks and resources and know-how. Attendees will hear real life case studies and success stories and learn about what collaborative models, practices and approaches have actually resulted in R&D innovations which promise great commercial success.

Registration & Coffee
08.30
Chairperson’s Opening Remarks
09.00

CSO/COO
Oncodesign, France

STRATEGIC APPROACHES & DRIVERS OF EXTERNAL INNOVATION

Flexible innovation models and how to measure partnering success
09.10
  • Bayer a global LifeScience Company
  • Partnering at Bayer Pharma, why and how?
  • Distinct Collaboration Models to leverage diverse Open Innovation opportunities at its best
  • Must-have KPIs to measure Successful Partnering

VP, Head of External Innovation Therapeutics
Bayer, Germany

Strengths and weaknesses of public private partnerships
09.50

Head of R&D G3O
Janssen, Belgium

Networking & Coffee Break
10.30
Interdisciplinarity as cornerstone of healthcare's future
11.00

Founder
Institute for Interdisciplinary Innovation in healthcare, Université Libre de Bruxelles, Belgium

HIGH-PERFORMING EXAMPLES OF EXTERNAL INNOVATION

Moving from in-house discovery to differentiation through identification
11.40

Director External Innovation, Oncology
Roche, Germany

Luncheon Break
12.20

BIOTECH PERSPECTIVES

External innovation technology company: A case study
13.20
  • Building the company: The bootstrapping model or “hybrid business model”
  • The integrated technology platform: A precision medicine drug discovery engine
  • Innovative asset creation: An example
  • Making the switch: From a technology CRO to a biopharmaceutical powerhouse

CSO/COO
Oncodesign, France

Collaborating with external partners
14.00
  • Nanocin platform: Improving cell and tissue delivery of reagents and drugs.
  • Building the company: advancing one technology in three sectors
  • Working with partners
  • Partner projects examples in drug development
  • In-house asset development approach

CSO
Tecrea, UK

Networking & Coffee Break
14.40
Panel discussion: New external innovation models for life sciences
15.10
  • Open-source and crowd-sourced R&D models: Examples
  • Private-public product development partnerships: Concrete examples for both EU and the US
  • Best practices in working with larger-scale R&D consortia: Organisation, coordination, practices, systems, technologies and people.
  • Partnering with technology companies: How emerging high-tech companies can forge win-win alliances with the life science industry via open innovation.

CSO
Tecrea, UK

Director External Innovation, Oncology
Roche, Germany

Closing remarks
15.50
End of day 2
16.00

Accelerating Discovery Through Advanced Analytics & AI

Day 2 - Stream 2 - 28th January, 2020

Stream Overview

This stream will focus on how to plan and implement data-driven approaches in the drug discovery process to unlock innovation. Huge volumes of raw data can be merged with other data sets, structured, and analysed from a myriad of perspectives, not just to achieve answers to complex research questions, but also to develop new hypotheses. Attendees will understand how a dedicated R&D data strategy for precision medicines and large “Omics” data volumes can achieve deep insights that enhance R&D decision making and innovation.

Registration & Coffee
08.00
Chairperson’s Opening Remarks
08.30

Head of Translational Medicine and Bioinformatics
Agenus

PRECISION MEDICINE IN ACTION

A collaborative machine learning approach to drug discovery and design
08.40

Senior Director Computational Biology, Discovery Sciences
Janssen Research & Development

Novel big data omics platform finds tumor-recognizing, tumor-specific T Cell Receptors (TCRs)
09.10

Head of Translational Medicine and Bioinformatics
Agenus

Towards an AI-powered validated multi-omics platform to support clinical biomarker research
09.40
  • To identify patient selection strategies for complex anti-cancer therapies it is key to thoroughly characterise tumors using a multi-omics approach.
  • A computational platform to enable efficient clinical biomarker research has to address analysis needs of different user groups like bioinformaticians & biostatisticians, translational scientists, clinical researchers.
  • Data from clinical studies need to be integrated with enormous amounts of public data
  • AI and machine learning capabilities are key to address challenges in genomic data processing and digital pathology
  • Through different analytical tool sets, each tailored to needs of user groups, biomarker research teams can jointly work on selected unique sources of biomarker data
Eike Staub

Director, Head of Oncology Bioinformatics
Merck

Networking & Coffee Break
10.10
RNA medicine meets systems biology: Precision medicine tools to optimise next generation drug development
10.40

We are in the dawn of a new era of RNA therapeutics in which precisely targeted RNA molecules exert powerful effects to selectively eliminate cancer cells, restore homeostasis or address disease processes with minimal side-effects. In addition, systems biology approaches to understanding function are supporting powerful new drug target discovery programmes. We explore both the possibilities and the reality of bringing together these novel paradigms to forge new high precision medicines.

Co-Director Noncoding RNA Core
Institute for RNA medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, USA

Metabolic phenotyping in medicine and personalised medicine
11.10

Professor of Pharmaceutical Technologies
University of Greenwich, UK

INNOVATIVE APPROACHES TO DRUG DISCOVERY

Creating a platform for querying external data for discovery
11.40

Over the last years, the commercially available chemical space (with pharmaceutical relevance) has rapidly increased.
Several providers today are offering catalogs consisting of several hundred millions of screening compounds.
We built a new compound platform to enable browsing, searching, selection, and ordering of compound sets from these libraries.
The platform offers these capabilities by standardizing and preprocessing all molecules, calculating relevant properties, and enabling access to these libraries by combining fast structure-based search with property and metadata filters.

ML/AI Lead, R&D Informatics, Small Molecule Discovery Informatics
Roche

Luncheon Break
12.10
CRISPR-based functional genomics: From data to drugs
13.10
  • Assessing the impact of CRISPR-based approaches to the drug discovery process
  • Evolution of analytical and informatics approaches: where less is more, and more is better
  • Understanding new data features and a new standard of data quality
  • Global harmonisation and application processes for a cleaner data repository

Head of Strategy
Horizon Discovery, UK

Histogenomics case study: Why and how to detect a tumor-driving molecular event in routine diagnosis data
13.40
  • Bayer Pharma R&D’s approach to Artificial Intelligence
  • AI & Medical Imaging, why now?
  • Histogenomics case study: Towards a more quantitative assessment of medical images
  • Lessons learned: How to bring a high risk, agile collaboration pilot towards productisation

Head of Decision Science, Digital Transformation & IT
Bayer

Industrialising early stage target discovery with deep-learning and high-content imaging
14.10
  • Early stage screens are shifting towards complex physiologically relevant models, with image-based readouts, yet this creates and image analysis nightmare
  • By using deep convolutional neural networks to analyse raw imaging data we can now effectively relive this bottle neck and run screens of thousands of conditions against complex multi-cellular and 3D models
  • In turn this has allowed us to identify novel targets involved in fibroblast activation that we are now developing and validating therapeutic antibodies against

CEO and Co-Founder
Phenomic AI

Networking & Coffee Break
14.40
Predictive analytics and machine learning in supporting ADME/PK optimization
15.10
  • ML models are developed to guide chemistry towards selective use of in vitro assays
  • Simplified data access and workflows drive efficiency in PK characterization
  • Advanced project specific data analysis and visualization tools support teams in decision making

Senior Investigator II, Modeling & Simulation, Data Science
Novartis

Panel Discussion: Impact of high-performance computing on drug discovery and translational science
15.40
  • Utilising Big Data, focusing specifically on two phases of research: discovery, translational.
  • Next-Generation Sequencing, proteomic & genomic Big Data as a source of developing new biomarkers & personalised medicines. How do we deal with the data bottleneck?
  • Precision medicine tools to optimise next generation drug development.
  • Data mining to discover potential in both new and old molecules

Senior Director Computational Biology, Discovery Sciences
Janssen Research & Development

Professor of Pharmaceutical Technologies
University of Greenwich, UK

CEO and Co-Founder
Phenomic AI

Head of Strategy
Horizon Discovery, UK

Closing remarks
16.20
End of day 2
16.30

Senior R&D executives: Scientific Officers, Chief Information Officers, Chief Technology Officers, Knowledge & Data Management (Discovery, Clinical & Real-World Data), R&D Analytics, Informatics, R&D Innovation, External Alliances & Innovation, R&D Strategy.

Drug Discovery: Drug Discovery, R&D, Lead Identification & Target Validation, Screening, Translational R&D, Genomics & Proteomics, Biomarker R&D, Senior Scientist, Biostatistics, Biometric, Precision Medicine, Personalised Medicine, Computational Biology

External Innovation: Business Development, Strategic Collaborations, Alliances, External Innovation, Consortia, Partnerships

R&D Analytics & AI: Data Analyst, Data Scientist, Bioinformatician, Bioinformatics, CIO, AI, Machine Learning

Media Partners

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Speaker Biographies

Rita Mateus Seidl

Director External Innovation, Oncology
Roche, Germany

Rita is Director of External Innovation for Oncology at Roche Pharmaceutical Research & Early Development. In her role she provides scientific evaluation of external opportunities for Oncology, leading the initial evaluations and interacting with cross functional lines to identify the most promising opportunities to pursue. She joined Roche as a Post-Doc in 2009 in the Oncology Discovery department and became a group leader in the same department in 2012, during which time she was pre-clinical leader of several portfolio projects, work which has granted a nomination for the Roche High Talent Pool. Rita holds a PhD in Human Biology by the Medical Faculty of the University of Porto and graduated in Biology at the Faculty of Sciences, University of Lisbon in 2002. Since early days she felt compelled to study cancer, reason why she joined the Portuguese Institute for Oncology in Lisbon for the degree’s final internship, and afterwards joined the team of Prof. Raquel Seruca at IPATIMUP in 2002. In 2004 Rita was awarded a 1-year Marie Curie fellowship, followed by a PhD fellowship from the Portuguese FCT to develop her PhD in collaboration between the University of Porto and the Technical University of Munich.  

Alexander Scheer

Chief Scientific Officer
ERYTECH Pharma, France

Alexander Scheer has more than 20 years of experience in R&D and the life science industry both in Pharma and Biotech. Prior to joining ERYTECH as Chief Scientific Officer in 2016, he was the Head of Research at Pierre Fabre in France, focused primarily on oncology and central nervous system research. Before, Dr. Scheer served as a Director, Global Research Informatics & Knowledge Management R&D and Project Leader, Neglected Diseases at Merck Serono in Switzerland where he led Merck’s program to develop drugs for neglected diseases in collaboration with the World Health Organization (WHO). At Serono, he served as Head of Molecular Screening and Cellular Pharmacology Department. Before joining industry, he was assistant professor at the University of Lausanne, Switzerland. Dr. Scheer holds M.Sc. in Chemistry from the University of Gottingen and a Ph.D from the German Cancer Research Center in Heidelberg

James Matcham

VP & Head of Early Biometrics and Statistical Innovation, Data Science and AI
AstraZeneca

James Matcham joined AstraZeneca in November 2013 as the Head of Early Clinical Development Biometrics, where he built the group specialising in early clinical trial design, decisions and analysis. He now leads the Early Biometrics and Statistical Innovation team. He started his career as a Research Fellow at the Applied Statistics Research Unit at the University of Kent, UK working for 5 years in various applications of statistics but particularly in the area of clinical cross-over trials, linear and non-linear modelling and Bayesian methods.  He then completed 21 years at Amgen where he worked on the development and regulatory/reimbursement approval of many of their biotechnology products, representing the company at regulatory submissions in the US and the EU. His last few years there were spent working to improve literature review, the use of adaptive and early phase design, network meta-analysis, Bayesian methods and quantitative decision making.

James is a Chartered Statistician of the Royal Statistical Society has been a member of UK society for Pharmaceutical Statisticians (PSI) for over 30 years, serving on the Scientific and Training Committees as well as the Board of Directors. He has also served on the Professional Affairs Committee of the Royal Statistical Society and the Scientific Committee of the European Federation of Pharmaceutical Statisticians.

Alexander Krupp

Head of Computational Life Science IT
Bayer

Dr. Alexander Krupp heads the department “Computational Life Science IT” for Research, Development, Drug Safety and Medical Affairs of Bayer Pharmaceuticals. His department focuses on integrating information across the value chain and on improving scientific and managerial insight generation by advanced analytics.

Dr. Krupp is passionate about bringing digital innovation to the pharmaceutical industry to enable the invention of novel medicines that will benefit millions of patients. His recent activities have comprised the creation of an architecture competency cluster, digital strategy definition as well as the introduction of processes and governance bodies to achieve this company goal.

Prior to his current position, he has consulted clients in the LifeScience industry in strategy, business process redesign, digital transformation, value stream analyses, carve out and portfolio optimization. Dr. Krupp holds a M.Sc. in Biochemistry and a PhD in Neuroscience. Beyond his technology background, his scientific expertise is focused on oncogenic signaling and growth factor receptor signaling as well as neurophysiology and the molecular basis for learning and memory.

Pieter Peeters

Senior Director Computational Biology, Discovery Sciences
Janssen Research & Development

Pieter Peeters is heading the European computational biology team in Discovery Sciences at Janssen Research & Development. His group is aiding the drug discovery and development teams in Janssen R&D in their search for novel safe and effective drugs by applying both computational as well as wet lab ‘omics approaches. The team is involved data and high content imaging based approaches aiming at comprehensive understanding of drug action.    

Pieter obtained his Ph.D. in Applied Biological Sciences (medical molecular biology) at the Center for Human Genetics from the Catholic University Leuven, Belgium and graduated as a bioengineering (gene and cell technology and interface chemistry) at the same university. During his PhD he studied the role of the ETS-variant gene 6 (ETV6) in different mechanisms for leukemogenesis. This research into the molecular causes of leukemia demonstrated for the first time a role for the JAK2 kinase in the etiology of myeloproliferative neoplasms and leukemias.

Pieter has been the Janssen lead for the ExaScience life lab, a collaborative effort between Intel, IMEC the 5 Flemish Universities and Janssen with the aim of expediting R&D in healthcare by applying high performance computing approaches. In addition, he was the Janssen lead for the Innovative Medicine Initiative project on the application of inducible pluripotent stem cells in drug discovery and drug safety testing (StemBANCC). Currently, his team is utilizing single cell analytical capabilities to enable the exploitation of the immune system for disease monitoring, interception and immunomodulation as well as advanced analytics and machine learning methods to for both evaluating and designing small molecules  expediting drug discovery.

Benoit Marchal

Senior IT Project Manager Specialized in Health IT
Roche, Switzerland

Benoît has an IT Master Degree from the University of Technology of Compiegne (France) and has more than 25 years’ experience leading various digitalization projects to improve and streamline the clinical research process. Before joining Roche, Benoît created and managed the startup NovaXon that provided solutions to pharmaceutical companies and hospitals to collect clinical data. Previously he worked for Medtronic in a special innovation department to explore new therapies with active medical devices. Most recently, he took the position of Roche representative in the industry collaboration EHR4CR and became a strong advocate both internally and externally of the potential of hospital real world data to support medical research. In parallel Benoît, is leading several innovation proposals to address some of the common challenges observed in precision medicine.

Theo Meert

Head of R&D G3O
Janssen, Belgium

Prof Theo F. Meert is head of the R&D Global Government Grant office (G3O) of J&J. He is also a professor and scientific advisor/researcher at different universities: Leuven, Antwerp, Brussels, Hasselt and Ghent.

During his career at J&J that started in 1981, Dr. Meert has been appointed to multiple international global functions. Within his various functions, he guided different multidisciplinary research teams in the field of CNS (Psychiatry - Addiction - Pain -Neurology/ Alzheimer). The activities of these groups covered the complete drug discovery process from early drug candidate selection to POC and further clinical testing. He was a key driver for several advanced projects in the CNS area leading to marketed drugs. Dr. Meert also supports some Full Development products and is involved in the scientific support of novel and marketed products. Dr. Meert has constructed an extensive network within J&J and external scientific and clinical organizations. He has also built an external network of external partnership initiatives and was instrumental in various novel external innovation models.

Dr. Meert’s scientific expertise is reflected in multiple patents (>15), publications (> 243), congress communications (> 200) and invited lectures (>190). Dr. Meert obtained a Ph.D. in psychopharmacology in Experimental Psychology at the University of Brussels (1986) and a Ph.D. in Medicine/Anesthesiology at the University of Antwerp (1994).

Elke Dittrich-Wengenroth

VP, Head of External Innovation Therapeutics
Bayer, Germany

Elke Dittrich-Wengenroth, Ph.D., is heading the function External Innovation Therapeutics at Bayer, Pharmaceuticals Division, as Vice President since October 2014. The R&D function’s mission is to ensure early access to breakthrough innovation to enable a sustainable, value-creating pipeline of innovative products by fostering external partnerships based on scientific excellence, mutual trust and successful alliance management.

Before she hold the position of a Global Program Head within Drug Discovery at Bayer HealthCare leading global, cross‐functional teams from preclinical development up to clinical Proof of Concept in different therapeutic areas e.g. Cardiology, Hematology, Ophthalmology and Gynecological Therapies.

Elke is a biologist by training and received her Ph.D. from the Rheinisch-Westfälische-Technische Hochschule Aachen, Germany. She started at Bayer R&D as a Lab‐Head identifiying new targets and lead compounds in cardiovascular indication areas. During that time she was also responsible for lead optimization project teams, optimizing first lead structures up to the identification of a clinical development candidate.

David Ruau

Head of Decision Science, Digital Transformation & IT
Bayer

David Ruau, PhD. is the global Head of Decision Science at Bayer Pharmaceuticals working across all business functions. David is an experienced leader in data science, quantitative biomedical and pharmaceutical research with 15+ years experience in various research area of bioinformatics and biomedical research.

Joerg Berghausen

Senior Investigator II, Modeling & Simulation, Data Science
Novartis

Joerg is leading the Data Science Team in the Pharmacokinetics Sciences section within Translation Medicine. He is a physico-chemist by training and has gained broad experience in supporting project teams during lead optimization. During his career in pharmaceutical industry, he worked on solid-state characterization, formulation support for PK and toxicological studies, determination of physico-chemical parameters and various ADME properties. He represented ADME and PK sciences in various project teams in discovery phase and got involved in data science and modeling due to his interest in ADME property models and PBPK predictions.

Abel Archundia-Pineda

Global Head of IT & Digital Transformation
Bayer, Germany

Abel joined Bayer July 2017, as head of IT for the Pharma division and member of Bayer Group IT Board.
Before joining Bayer, Abel was Global CIO,  Sandoz Division (Generics, 2012-) as well as head of IT for Novartis Technical Operations (~85 plants) looking after manufacturing, supply chain and quality (2015-) and member of the Novatis IT Board. In sum, Abel has ran IT at Big Pharma for over ten years.
Positions prior to Novartis include Cemex (CIO Europe-Asia from Madrid),  Dell (General Manager, Mexico, and Supply Chain, Latin America) and Boston Consulting Group (Principal, Monterrey and Dallas offices).  He holds a degree in electronics engineering from Tec de Monterrey, Mexico, and an MBA and Public Management degree from Stanford Graduate School of Business.

Abel is married and has two children, young men who keep him on his toes. He enjoys sports like competitive rowing and swimming, loves the outdoors and is a lousy golfer.

Michael Lange

ML/AI Lead, R&D Informatics, Small Molecule Discovery Informatics
Roche

Michael joined Roche in September 2018 as an ML/AI Lead. In this role, he is responsible for driving the Lab Automation. Before joining Roche, Michael worked already as consultant for Roche and also for other companies with a particular focus on data integration.

Liam Good

CSO
Tecrea, UK

Liam is a founding Director at Tecrea Ltd. Liam’s first post graduate employment was within wineries and breweries, where he developed a passion for microbiology. He next completed a PhD in Canada on yeast genetics and then postdoctoral training at the Department of Cell and Molecular Medicine at the Panum Institute in Copenhagen. Liam was next a group leader at the Department of Cellular and Molecular Biology at the Karolinska Institute in Stockholm. Liam is now a Professor of Microbiology and Biotechnology and Dean for Innovation at the Royal Veterinary College, University of London. Liam sits on several scientific advisory and strategy boards.  His research and innovation interests include nanomedicine, antimicrobials, antimicrobial resistance and cellular delivery technologies.

Jan Hoflack

CSO/COO
Oncodesign, France

Dr. Hoflack is the CSO/COO of Oncodesign S.A., a France based biotechnology company, with over 32 years’ experience in the field of Drug Discovery and Development in international companies. Jan moved into the small life science company world after 22 years as a senior executive in major pharma companies (Sanofi, Novartis, AstraZeneca, Johnson & Johnson). He is a strong believer in the open innovation model, based on productive partnerships that combine the strengths of "big pharma" and small innovation companies. As creator of the Nanocyclix medicinal chemistry platform for next generation macrocyclic kinase inhibitors, Dr Hoflack initiated multiple international collaborations around Oncodesign’s probe based drug discovery process. Following Oncodesign’s IPO in 2014, the company is  advancing a number of internal programs on unexplored and intractable kinases with high potential in oncology, neurology and inflammatory diseases. In 2016 these programs were strongly accelerated following the acquisition of a former GSK R&D site in Paris, France. Oncodesign is now established as a leader in next generation kinase inhibitors, and as an emerging and sustainable biopharmaceutical company.

John Castle

Head of Translational Medicine and Bioinformatics
Agenus

Dr. John Castle is Associate Vice President, Head of Translational Sciences, at Agenus, Inc. Dr. Castle has deep expertise in biomarkers and therapy development using computational immunology, bioinformatics, biotechnology, and genomics. Having built translational bioinformatics and genomics units focused on immunotherapies, Dr. Castle pioneered the computational approach to neoantigen identification for anti-tumor immunity. His bioinformatics approach has revolutionized neoantigen vaccine platforms and is used for TCR target selection and response biomarkers. Prior to joining Agenus, he served as associate director at Rosetta Inpharmatics/Merck & Co. and subsequently as the co-director at the Biomarker Development Center of Translational Oncology at the University of Mainz, Germany. Dr. Castle was the director of bioinformatics at BioNTech AG (DE). Dr. Castle studied physics at Rice University (U.S.), in Göttingen (DE) , and in Canberra (Fulbright to AUS) and received a Ph.D. in geophysics from the University of Washington in Seattle.

Sinanudin Omerhodzic

CIO
Hartmann Group, Germany

Born in Berlin. Graduate IT on Technical University of Berlin.
Experienced Technology Leader in setup of corporate digital technology innovation teams with the entrepreneur mindset (“act as a growth accelerator by proactively utilize modern technologies to implement new business models) for different industries such as healthcare, automotive, airspace and industry.

Hobbies: Soccer trainer and compose music on piano

Career Path:

CIO & Senior Vice President, Paul HARTMANN AG (actual role since January 2017)
Business Technology Leader EMEA, Johnson & Johnson (2015 - 2017)
Global IT Director, Trelleborg (2011 - 2015)
Head of IT, Sonova Holding (2008 – 2011)
Head of IT Europe, Sonic Innovation (2003 – 2008)

Nazar Rasul

Global Head of Technology & Innovation Management
Siemens Healthcare

Nazar has been within Siemens since more than 15 years, with strong professional background in R&D, technology and digitalization strategy, realization of digital agenda, strategic innovations on corporate level, industrial and healthcare IT, innovation program management.

His current position is Global Head of Technology & Innovation Management within company CTO organization. He used to work several years until 2015 for Siemens Corporate Technology within Strategic Marketing&Visioning as Project Director with focus on strategic innovation management and future visions.

Between 2003 and 2009 he was Head of SW development within Medical Electronics and Imaging Solutions at Siemens Healthcare in Germany. He started his carrier earlier at Siemens Medical Solutions in Sweden as Technical Project Manager for Angiography systems for cardiology and neurology applications.

He holds a Ph.D. degree in Engineering / Automated systems and an MBA in General Management.

Jeremy Everett

Professor of Pharmaceutical Technologies
University of Greenwich, UK

Jeremy Everett is the Professor of Pharmaceutical Technologies at the University of Greenwich UK. In addition, he is a Visiting Professor in the Department of Surgery and Cancer at Imperial College and at the Lee Kong Chian School of Medicine at Nanyang Technological University, Singapore, where he is also a Scientific Consultant.

He previously held a variety of global drug discovery technology leadership positions for Pfizer and SmithKline Beecham, including responsibility for drug target analysis, drug design, drug lead generation, analytical sciences, biobanking, screening file management, high throughput screening (HTS), and structural biology. He is a consultant on drug discovery and on pharmaceutical patent litigation.

Jeremy conducts research in metabonomics and pharmaco-metabonomics, in which he has worked for over 30 years, including co-naming and defining both areas. He is a co-discoverer of pharmacometabonomics. Current work is focused on genotype – metabotype correlations in the areas of obesity and ageing.

Jeremy received both his BSc and PhD in chemistry from Nottingham University, UK. He did post-doctoral studies at McMaster University and at McGill University in Canada.

Jeremy is a Fellow of the Royal Society of Chemistry and a Chartered Chemist, a Member of the American Chemical Society, a Fellow of the Higher Education Academy and is an author or co-author on 99 peer-reviewed publications and several patents, with over 4,400 citations to date and an h-index of 29. He has delivered over 60 invited lectures.

Winston Hide

Co-Director Noncoding RNA Core
Institute for RNA medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, USA

Hide performed post-doctoral training in molecular evolution at the University of Texas in Houston with Wen Hsuing Li, also at Baylor College of Medicine at Human Genome Centre with Richard Gibbs and also at the Smithsonian Museum of Natural History in Washington DC. His first paper, published in Nature, was a controversial analysis of rodent evolution - using molecular phylogenetics he questioned the membership of guinea-pigs in the rodentia.

 

His career began as a director of genomics at MasPar high performance computer corporation in Silicon Valley, California. Returning to South Africa to found and direct the South African National Bioinformatics Institute (SANBI) at the University of Western Cape in 1996, he established the first PhD programme in Bioinformatics in Africa and is a founder of the African Society of Bioinformatics and Computational Biology and was the first African on the board of the International Society of Computational Biology. At SANBI he founded the Medical Research Council Unit for Bioinformatics Capacity Development and established the WHO regional Training Center for bioinformatics. An author of the National Biotechnology Strategy for South Africa he founded the South African National Bioinformatics Network. Focusing on the development of Africa’s peoples he is a founder member of the steering committee that established the NIH-Wellcome Trust funded Pan African H3 Africa Genome Initiative. Together with a group from the World Health Organisation, Yale University, and the UK Sanger Center he established the International Glossina Genome Initiative in 2005 which culminated in the publication of the Tsetse Fly genome in 2014.

Hide has been recognised for these activities by receipt of the first International Society for Computational Biology award for outstanding achievement.

As Associate Professor of Bioinformatics and Computational Biology in the Department of Biostatistics at Harvard School of Public Health he has led development of personal genomics approaches to public health and directed the Center for Health Bioinformatics. Hide developed the bioinformatics strategy for the Harvard Stem Cell Institute and was Director of its Center for Stem Cell Bioinformatics where he built a science commons for data sharing and integration.

After 4 years as Chair in Computational Biology at the University of Sheffield Institute for Translational Neurosciences where he drove of systems approaches to genome medicine as Director of the Centre for Genome Translation, Hide has recently returned to Harvard.

His research at Beth Israel Deaconess Medical Center now addresses systems biology of RNA medicine to deliver clinical translation of genomics for application to repurposing of drugs, to determine prioritised drug targets and to deliver prediction to predisposition to disease. He uses standardized approaches to discovery in complex neurodegenerative diseases such as Alzheimer’s. Hide directs the bioinformatics for the Alzhiemer’s Genome Project  (Cure Alzhiemer’s Foundation) where he has built the computational infrastructure for, and analyzed 1400 whole genome sequences from patients with the disease and is a driving member of the CureAD CIRCUITS consortium, a group made up of scientists from Harvard, MIT and UCSF funded by the Cure Alzhiemer’s Foundation to determine the regulatory processes that go awry in Alzheimer’s.

Honours: Hide has received the South African National Research Foundation Presidents’ award, the Oppenheimer Trust Sabbatical Award and the first International Society for Computational Biology; Outstanding Achievement award.

Academies: Elected member of the Academy of Science of South Africa.

Michel Goldman

Founder
Institute for Interdisciplinary Innovation in healthcare, Université Libre de Bruxelles, Belgium

Michel Goldman (born 1 January 1955) is a Belgian medical doctor specialized in immunology and internal medicine. He is the Founder and  co-Director of the Institute for Interdisciplinary Innovation in healthcare and a Professor of immunology at the Université libre de Bruxelles (ULB).

He was the first Executive Director of the Innovative Medicines Initiative Joint Undertaking (IMI), from 2009 to 2014. With a €2 billion budget provided jointly by the European Federation of Pharmaceutical Industries and Associations and the European Commission, he was responsible for 59 public-private consortia in areas of major importance, including antimicrobial resistance, Alzheimer's dementia, autism, diabetes, immuno-inflammatory disorders, chronic pulmonary diseases and drug safety. During his mandate, he established privileged contacts with major European academic centers as well as large pharmaceutical companies and biotech companies active in healthcare worldwide.


From 1990 to 2008, he was the Director of the Department of Immunology-Hematology-Transfusion at the Erasme Hospital in Brussels and from 2009 to 2014 he serves as the first Director of the Institute for Medical Immunology at ULB.

 

Besides his academic duties, Michel Goldman is the Editor-in-Chief of Frontiers in Medicine, a Senior Fellow of Fastercures, a branch of the Milken Institute, a member of the Board of the European Tuberculosis Vaccine Initiative, of the Scientific Board of the Quebec - Clinical Research Organization in Cancer (Q-CROC), and of the Governing Board of the French National Institute of Health and Medical Research (INSERM).

Michel Goldman’s scientific achievements resulted in more than 400 articles in peer-reviewed journals and the Thomson Institute recognized him as ISI Highly Cited Scientist for Scientific Information. In 1992, he shared the Lucien Steinberg Prize with Pr. Peter Piot. In 2000, he was the laureate of the Quinquennial Prize of the Belgian National Fund of Scientific Research for Clinical Sciences. He held in 2001 the Spinoza chair at the University of Amsterdam. In 2007, Michel Goldman was awarded the degree of Doctor Honoris Causa of the Université of Lille.

Loubna Bouarfa

EU AI High Level Expert Group Member
Founder & CEO, OKRA Technologies

Loubna is an AI and ML expert as well as Founder and CEO of OKRA Technologies. Loubna is currently a member of the European Union High-Level Expert Group on Artificial Intelligence, where she is particularly focused on healthcare and achieving competitive business impact with AI. She was named an MIT Technology Review Top Innovator Under 35, a Forbes 50 Top Women In Tech, and recently won the prize for Best Female-Led Startup at the StartUp Europe Awards. 

Elena Bonfiglioli

Regional Business Leader Health and Life Sciences EMEA
Microsoft

As lead for Health and Life Sciences, Elena is responsible to drive strategy, advance the digital transformation agenda with health and pharma customers, and represent Microsoft’s industry position, working together with a community of over 250+ professionals across the EMEA region.

Over the last ten years, Elena has been a proactive contributor in the areas of healthcare policy, health-tech innovation, and multi-stakeholder partnerships.  In July 2017, Elena was elected to the HIMSS Europe Governing Council.

Elena spearheaded key initiatives on Health 4.0 and health digital transformation.  Mobilizing a core group of industry stakeholders, Elena started the European Cloud in Health Advisory Council, a vendor-neutral C-level forum aimed to foster cloud-first innovation in the health sector. The Council promoted two Calls to Action: one on Health Data Saving Lives and Protecting Patients’ Rights (eHealth Week 2017); and Trust in the Cloud, leading with cloud-first policies (eHealth Week 2016).

In 2013, working with a group of leading e-Health partners, Elena led two industry-wide go to market and advocacy positions on innovative health services; the Manifesto for a Healthier Europe and Healthier Cities.

From 2007-2012, Elena held the role of Senior Director Health and Education Policy in Europe, when she led the creation of the Employability Alliance aimed to empower 20 Mil people with Skills for New Jobs.

Elena started at Microsoft in February 2003 as Director of Corporate Affairs and Corporate Responsibility with the task to define Microsoft CSR strategy and corporate philanthropy programs.  She is the co-founder and Board Member of the Women in Leadership (WiL) Network, a joint effort between Microsoft, INSEAD and the Women Forum.

Before joining Microsoft, Elena worked for CSR Europe as Director of Corporate Programs - in charge of stakeholder engagement and CSR initiatives across member companies; actively contributing to the development of the CSR agenda at international level.  Elena co-founded the European Academy of Business in Society where she served as interim Executive Director.

Elena is part and founding member of the Centre for Evolutionary Learning CEL, a network of academic and management professionals devoted to empowering organizational and executive development through meditation and innovative learning practices.

Grazia Frontoso

Data Analytics Specialist
Google Cloud, Switzerland

Grazia Frontoso is a Data Analytics Specialist at Google Cloud in charge of supporting enterprise customers in Switzerland in digital transformation and Big Data analytics for the healthcare & life science sector. Before joining Google, she worked for several years as Software Product manager in risk management designing cloud solutions for regulated industries. She holds a PhD in physics and is passionate about the transformational power of technology.

Sam Cooper

CEO and Co-Founder
Phenomic AI

Sam recently finished his PhD at Imperial College London and the Institute of cancer research, under the supervision of Prof. Robert Glen an early pioneer of chemoinformatics, and Dr. Chris Bakal a leader in high-content screening. Over this period Sam used novel machine learning methods to answer questions in biology and drug discovery, publishing 12 times over a 4-year period, and winning industry led competitions. During this time, he also organized conferences in the field and met Oren Kraus, his co-founder at Phenomic AI and one of the first researchers to use deep-learning on biological data. Together they set-up Phenomic AI an early stage biotech, based in Toronto, backed by $2.25m in Silicon Valley and Canadian VC funding, and with >$1m in industry contracts. Phenomic is now racing to commercialize a platform for high-content screening of therapeutic Ab, that integrates wet-lab automation with state-of-the-art analysis techniques. 

Brian Burke

Head of Strategy
Horizon Discovery, UK

Brian joined Horizon in August 2012 as a Business Development Manager and was promoted to Global Head of Strategy during 2018. In this role, he is responsible for driving strategic development and execution across the Horizon business. He works closely with other functions to analyse and impact the wider Horizon opportunity in order to build value more effectively.

Before joining Horizon, Brian worked successfully in a number of commercial and licensing roles with a particular focus on gene editing, bioproduction and next generation sequencing. Prior to moving to industry, he gained a first class honours degree from the University of Glasgow and a PhD from Leeds University.

Previous Attendees at R&D Data Intelligence Leaders Forum - Basel, Switzerland, 2019

Company
Job Title
2KMM
CEO
2KMM
Data Management and Analysis Assistant
Almirall S.A
Molecular Informatics R&D Specialist
Almirall S.A
R&D IT Business Partner & SVC Delivery
Amgen Switzerland
Medical Director
aparito
Founder & CEO
Bayer
IT Business Partner
Bayer
IT Business Partner Research
Bayer
Director, Medicinal Chemistry
Bayer Business Services GmbH
IT Business Partner Medical Affairs & Pharmacovigilance
Bayer Consumer Care
Digital GxP Compliance Manager
Biogen
Principal Scientist
Boehringer Ingelheim
IT Architect
Catholic University of Korea
Professor
Center for Research and Interdisciplinarity (CRI)
Managing Director
ChemAxon
Account Manager
ChemAxon
Senior Application Scientist
CSL Behring
Head Breakthrough Technologies
CureVac
Co-founder and Chairman of the Supervisory Board
Dacadoo
President and CEO
Databricks
Life Sciences Lead
Deloitte ConvergeHEALTH
Senior Manager
Deloitte UK Centre for Health Solutions
Research Manager
DNAnexus
CEO
docdok.health
Co-Founder & CEO
e-therapeutics
Head of Discovery Informatics
European Connected Health Alliance
Chair
Evonetix
CEO
Exscientia
Head of Chemoinformatics
F. Hoffmann-La Roche
Biology Workflow Team Leader
F. Hoffmann-La Roche
Head of Small Molecule Discovery Workflows
F. Hoffmann-La Roche
Research Informatics Scientist
F. Hoffmann-La Roche
Principal Scientist
F. Hoffmann-La Roche
Senior Scientist
F. Hoffmann-La Roche
Personalised Healthcare CoE
F. Hoffmann-La Roche AG
Head of Business Intelligence Finance, Operations, Site Services, Q&R Analytics
F. Hoffmann-La Roche Ltd
Group Manager EU/International Clinical Trial Regulatory Management
FeetMe
Co-founder and CEO
GE Healthcare
Global Digital Services Transformation Leader
Genedata
Business Development Manager
Getinge
Systems Architect
Google Cloud
Sr. Program Manager, Healthcare & Life Sciences
GSK
Head Computational Biology and Stats
Helbling
Head of Development
Helbling
Development Engineer
Hoffmann La Roche
Strategic Analytics Manager
icometrix
CEO
Idorsia Pharmaceuticals
Head of Translational Science
Iktos
Founder and CEO
Iktos
CSO
Image Analysis Group
CEO
Insilico Medicine
CTO
Intellegens
CTO
Janssen Pharmaceuticals
Senior Associate Scientist
Johnson & Johnson
Associate Director Integrated Clinical & Operational Analytics
Linguamatics
Senior Account Manager, Europe
Lupus Friends and Family Foundation
Founder & President
Medisafe
VP Pharma (EMEA)
Medtronic
EMEA privacy consultant
Merck Sharp and Dohme
Senior Vice President and Head Global Clinical Development, Chief Medical Officer
Nebion
CEO
Nebula Genomics
Co-founder
NHS Foundation Trust
Director of Innovation and Development
Novartis
Global Head Technology, Architecture, Digital Drug Development
Novartis
Associate Director, Information Systems
Novartis
Global Head of Portfolio Management, Medical, Digital and RWE Solutions
Novartis
Asc. Director Knowledge Management
Novartis
Data Science & A.I. Technical Advisor
Novartis
Head Data Governance
Novo Nordisk A/S
Senior Director
Novo Nordisk A/S
Head of Non-clinical Data Management
Novozymes
R&D Director, BioEnergy
Novozymes
Group Leader, Automation and Digitalization, R&D
Numerate
CSO
Philips
Principal Scientist - Medical Biomarker Research Oncology
Philips Research
Vice President, Member Program Board Healthcare Healthcare Strategic Partnerships
Pierre Fabre
BioInformatics Platform Director
Pool Global Partners
Entrepreneur in Residence
Pool Global Partners, USA
Founder and Managing Partner
Quantitative Biology Center Tübingen
Centre Head
Roche
Senior IT Project Manager Specialized in Health IT
Roche
Group Head Clinical Trials, Regulatory Management
Roche
Principal Scientist, Toxicology Project Leader
Roche Innovation Center Basel, Switzerland
Principal Scientist, Scientifc Information Management
Sanofi
Director of scientific relations R&D Europe
Shivom
Founder & CSO
Siemens Healthineers
Head of Digital Technology & Innovation
Technical University Dresden
Professor in Bioinformatics, BIOTEC and Dept. of Computing
TheraPanacea
Chief Executive Officer / Chief Scientist
Thomas Jefferson University and Jefferson Health System
Chief Digital Officer and Senior Vice President for Technology Innovation and Consumer Experience
University of Colorado
Distinguished Professor
University of Southampton
Research Fellow , Clinical Informatics Research Unit
University of Surrey
Professor of Machine Intelligence
University of Zurich
Professor of Bioinformatics, Institute of Molecular Life Sciences (IMLS) and Swiss Institute of Bioinformatics (SIB)
Zebra Medical Vision
Co-Founder and CTO

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Executive Vice President and Chief Digital Officer
Jefferson Health, USA

 

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Head of Clinical Development Integration Competency Center
Actelion
 

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SVP Clinical Development & Chief Medical Officer,
Merck & Co

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